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← All articlesCarrying excess weight affects more than appearance. It raises the risk of type 2 diabetes, heart disease, high blood pressure, joint pain, and sleep apnea. For years, patients across the San Fernando Valley had two real options: restrictive diets that rarely lasted, or surgery that felt like overkill for their situation. Medical weight loss closes that gap. At Contour Medical Clinic in Tarzana, physician-supervised programs pair FDA-approved GLP-1 medications, Semaglutide and Tirzepatide, with lab monitoring, nutrition guidance, and a plan built around each patient's health history rather than a one-size-fits-all protocol.
Semaglutide and Tirzepatide belong to a class of medications called GLP-1 receptor agonists. They mimic a hormone your body already produces to regulate appetite and blood sugar. In practice, that means patients feel fuller sooner, think about food less often, and digest meals more slowly, which adds up to steady, sustainable fat loss rather than the rapid rebound weight seen with crash diets.
In the STEP 1 clinical trial, patients using semaglutide lost an average of 14.9% of their body weight over roughly 16 to 18 months, using once-weekly injections with a gradual dose titration to minimize side effects.
Tirzepatide acts on two hormone pathways instead of one, GLP-1 and GIP, and the SURMOUNT-1 trial recorded an average 20.9% body weight reduction, the higher end of what is currently achievable with medication alone. The American College of Physicians now recognizes both semaglutide and tirzepatide as first-line pharmaceutical options for adults with a BMI of 30 or higher.
Medical weight loss is generally appropriate if your BMI is 30 or above, or if your BMI is 27 or above and you have a weight-related condition such as high blood pressure, type 2 diabetes, high cholesterol, or joint pain.
Certain conditions, including a personal or family history of specific thyroid tumors, pancreatitis, pregnancy or breastfeeding, and some kidney or liver conditions, may rule out GLP-1 therapy or require closer monitoring. That is why every program at Contour Medical Clinic starts with a full intake: health history, current medications, prior weight-loss attempts, and baseline labs, so your care team can confirm candidacy before you start.
GLP-1 medications are effective, but they are not a set-it-and-forget-it treatment. A supervised program means a clinician reviews your history first, screening for contraindications and interactions with current medications. Baseline and follow-up labs track your metabolic markers and catch issues early. Dose titration guidance starts you low and increases gradually to reduce nausea and other gastrointestinal side effects. Injection technique training builds your confidence administering your own weekly dose, and ongoing check-ins adjust the plan as your weight, labs, and goals change.
This is where supervised care shows a real advantage. Side effects like nausea and constipation are common early on, and having a clinician who can adjust the dose or timeline, backed by on-site labs, tends to resolve those issues considerably faster than going it alone through a telehealth-only service.
Medication accelerates weight loss, but it works best paired with a plan for the metabolic side of the equation: body composition tracking, nutrition guidance that protects lean muscle mass (a common concern with rapid GLP-1-driven weight loss), and a long-term maintenance strategy for after you reach your goal weight. That is the difference between a shot that makes you lose weight and a coordinated medical program built to keep the weight off.
Your first visit is a consultation, not a prescription pad. Expect a conversation about your weight history, current health, and goals; a physical exam and baseline labs if needed; a clear explanation of Semaglutide versus Tirzepatide and which fits your situation; and a straightforward look at cost, timeline, and what results are realistic for you specifically.
Clinical trial averages range from about 15% of body weight with semaglutide to up to 21% with tirzepatide over 12 to 18 months, though individual results vary based on starting weight, dose, and adherence.
The most common side effects are gastrointestinal, including nausea, constipation, or mild fatigue, and are typically most noticeable during dose increases. Physician-supervised titration is specifically designed to keep these manageable.
That is a conversation for your care team based on your response, goals, and health history. Some patients transition to a lower maintenance dose; others focus on nutrition and lifestyle changes to sustain their results after completing treatment.
Coverage varies by plan and diagnosis. Our team can walk you through your options during your consultation, including current program pricing.
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If diets haven't worked and you're ready for a plan built around your actual biology, Contour Medical Clinic's Medical Weight Loss program in Tarzana combines Semaglutide and Tirzepatide with physician oversight, lab monitoring, and a plan that adapts as you progress. Serving Tarzana, Woodland Hills, Encino, and the greater San Fernando Valley, our team is ready to help you take the first step. Schedule your consultation today.